Studies about CBD: the CBD / THC ratio

The hemp plant is a plant species that is very rich in different chemical substances and has a large quantity of cannabinoids, such as cannabinol, cannabigerol and tetrahydrocannabivarin; of these, THC and CBD are certainly the ones that stand out in terms of quantity in cannabis inflorescences, but over time it has been a major challenge to consider them separately. This has also had significant consequences in terms of raising awareness of the totally different effects of each on humans.

The two main phytocannabinoids, THC and CBD, have valid and different therapeutic properties; thus, taking them individually or together will produce other effects on the patient’s physique.

Since CBD and THC are the predominant cannabinoids in the plant, much of the scientific research so far has focused on their study and their relationship in therapy, i.e., on the THC: CBD ratio.

However, we must not forget the presence, in the phytocomplex of cannabis, of other cannabinoids with promising medicinal applications, such as cannabigerol CBG and cannabichromene CBC.

Besides, if you are new to CBD, you can discover the beginner guide to CBD by following this link.

Photo by HempCrew on Unsplash


THC acts as :

  • antiemetic
  • anti-inflammatory
  • analgesic

Its intake also causes the classic sensation of “high”, traditionally associated with the recreational use of cannabis. So with a higher CBD: THC ratio (i.e., higher concentrations of CBD in proportion to THC), some of this head-in-the-clouds effect can be prevented.


CBD shares some of THC’s potential, but also acts as :

  • anxiolytic
  • anticonvulsant
  • antipsychotic

However, CBD does not produce the “high” sensation as THC does. For this reason, many patients on cannabinoid treatment begin their therapy (recommended and under medical prescription) with genetics and extractions low in THC and a very high CBD: THC ratio, such as Bedrolite. This allows preventing the psychotropic effects of THC while the patient becomes familiar with the substance.


Both phytocannabinoids have cancer-related therapeutic properties. While CBD can balance the psychotropic effects of THC, it has both analgesic and potentially valuable properties in the fight against cancer. CBD can also reduce anxiety and a rapid heartbeat that can be induced by THC intoxication. Thus, THC and CBD can work synergistically to produce the desired effects.

As a CB1 receptor antagonist, CBD modulates specific effects of THC, such as:

  • paranoia
  • anxiety
  • tachycardia
  • “High”

The essential difference between CBD and THC lies in how these molecules bind to cannabinoid receptors in the body. For example, THC binds to CB1 receptors while CBD binds to CB2. Different ratios of THC and CBD will therefore have other effects on the physique.


Changing the CBD: THC ratio can have an impact on the way cannabis interacts with the physique. Research is still in its infancy and ongoing, but this is a brief overview of the main THC: CBD ratios.

  • CBD / THC RATIO 0: 1

Consuming genetics and products with only THC will most likely experience the “high” effect of cannabis, its psychotropic character. Some may find it pleasant, as others may have problems managing it, especially initially. However, many patients find it challenging to approach a THC-only therapy.

Products high in THC induce states of euphoria, relief, and joy. But, unfortunately, they can also cause laughter and dizziness.

  • CBD / THC 1: 0

Genetics and products with this relationship do not produce a psychotropic or “high” effect, but positively affect the mood. In addition to these features, they provide a tool with significant therapeutic potential in treating drug-resistant epilepsy and mood disorders.

  • CBD: THC 1: 1

The presence of CBD and THC in equal measure (1: 1 ratio) typically produces very mild psychotropic effects. The 1: 1 ratio has been identified as the best in treating certain conditions such as cancer, insomnia, autism, fibromyalgia and neurological disorders such as multiple sclerosis.

A cannabis strain with a CBD: THC ratio of 1: 1 provides a minimal high effect, promoting relaxation, calm, and tranquillity. However, there are some, albeit minimal, adverse effects.


Some patients with depression, anxiety, paediatric seizure disorder and spasms have achieved good results with moderate doses of the product with a CBD / THC ratio greater than 10 to 1 or cannabis genetics high in CBD.

It gives you a general idea of how CBD and THC work together! And, if you want to buy the best CBD oils and other CBD products online, head to It is the leading online CBD supplier with the best products and services.

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